Caricamento...
Proton-sensing G protein-coupled receptors: detectors of tumor acidosis and candidate drug targets
Cells in tumor microenvironments (TMEs) use several mechanisms to sense their low pH (<7.0), including via proton-sensing G protein-coupled receptors (psGPCRs): GPR4, GPR65/TDAG8, GPR68/OGR1 and GPR132/G2A. Numerous cancers have increased expression of psGPCRs. The psGPCRs may contribute to featu...
Salvato in:
| Pubblicato in: | Future Med Chem |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Newlands Press Ltd
2020
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7607387/ https://ncbi.nlm.nih.gov/pubmed/32116003 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc-2019-0357 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|