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GPR68: An Emerging Drug Target in Cancer

GPR68 (or ovarian cancer G protein-coupled receptor 1, OGR1) is a proton-sensing G-protein-coupled receptor (GPCR) that responds to extracellular acidity and regulates a variety of cellular functions. Acidosis is considered a defining hallmark of the tumor microenvironment (TME). GPR68 expression is...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Wiley, Shu Z., Sriram, Krishna, Salmerón, Cristina, Insel, Paul A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6386835/
https://ncbi.nlm.nih.gov/pubmed/30696114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20030559
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