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GPCRomics: An approach to discover GPCR drug targets
G protein-coupled receptors (GPCRs) are targets for ~35% of approved drugs but only ~15% of the ~800 human GPCRs are currently such targets. GPCRomics, the use of unbiased, hypothesis-generating methods (e.g., RNA-sequencing [RNA-seq]), with tissues and cell types to identify and quantify GPCR expre...
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| Publicado no: | Trends Pharmacol Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6604616/ https://ncbi.nlm.nih.gov/pubmed/31078319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.04.001 |
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