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Detection and Quantification of GPCR mRNA: An Assessment and Implications of Data from High-Content Methods

[Image: see text] G protein-coupled receptors (GPCRs) are the largest family of membrane receptors and targets for approved drugs. The analysis of GPCR expression is, thus, important for drug discovery and typically involves messenger RNA (mRNA)-based methods. We compared transcriptomic complementar...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Sriram, Krishna, Wiley, Shu Z., Moyung, Kevin, Gorr, Matthew W., Salmerón, Cristina, Marucut, Jordin, French, Randall P., Lowy, Andrew M., Insel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796235/
https://ncbi.nlm.nih.gov/pubmed/31646252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02811
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