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G Protein-Coupled Receptors as Targets for Approved Drugs: How Many Targets and How Many Drugs?

Estimates vary regarding the number of G protein-coupled receptors (GPCRs), the largest family of membrane receptors that are targeted by approved drugs, and the number of such drugs that target GPCRs. We review current knowledge regarding GPCRs as drug targets by integrating data from public databa...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Sriram, Krishna, Insel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820538/
https://ncbi.nlm.nih.gov/pubmed/29298813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.117.111062
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