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Orphan G-protein-coupled receptors: the next generation of drug targets?

The pharmaceutical industry has readily embraced genomics to provide it with new targets for drug discovery. Large scale DNA sequencing has allowed the identification of a plethora of DNA sequences distantly related to known G protein-coupled receptors (GPCRs), a superfamily of receptors that have a...

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Detalhes bibliográficos
Main Authors: Wilson, Shelagh, Bergsma, Derk J, Chambers, Jon K, Muir, Alison I, Fantom, Kenneth G M, Ellis, Catherine, Murdock, Paul R, Herrity, Nicole C, Stadel, Jeffrey M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1565744/
https://ncbi.nlm.nih.gov/pubmed/9884064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702238
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