Discovery of the first potent proteolysis targeting chimera (PROTAC) degrader of indoleamine 2,3-dioxygenase 1

Cancer immunotherapy is revolutionizing oncology and has emerged as a promising strategy for the treatment of multiple cancers. Indoleamine 2,3-dioxygenase 1 (IDO1), an immune checkpoint, plays an important role in tumor immune escape through the regulation of multiple immune cells and has been rega...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Pharm Sin B
Main Authors: Hu, Mingxing, Zhou, Weilin, Wang, Yijie, Yao, Dongping, Ye, Tinghong, Yao, Yuqin, Chen, Bin, Liu, Gongping, Yang, Xifei, Wang, Wei, Xie, Yongmei
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606109/
https://ncbi.nlm.nih.gov/pubmed/33163345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2020.02.010
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados