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Activation of the CARD8 Inflammasome Requires a Disordered Region
Several cytosolic pattern-recognition receptors (PRRs) form multiprotein complexes called canonical inflammasomes in response to intracellular danger signals. Canonical inflammasomes recruit and activate caspase-1 (CASP1), which in turn cleaves and activates inflammatory cytokines and gasdermin D (G...
Guardat en:
| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7594595/ https://ncbi.nlm.nih.gov/pubmed/33053349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108264 |
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