The chemokine X-factor: Structure-function analysis of the CXC motif at CXCR4 and ACKR3

The human chemokine family consists of 46 protein ligands that induce chemotactic cell migration by activating a family of 23 G protein–coupled receptors. The two major chemokine subfamilies, CC and CXC, bind distinct receptor subsets. A sequence motif defining these families, the X position in the...

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Udgivet i:J Biol Chem
Main Authors: Wedemeyer, Michael J., Mahn, Sarah A., Getschman, Anthony E., Crawford, Kyler S., Peterson, Francis C., Marchese, Adriano, McCorvy, John D., Volkman, Brian F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2020
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7535910/
https://ncbi.nlm.nih.gov/pubmed/32788219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.014244
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