Chargement en cours...
Dual Targeting of the Chemokine Receptors CXCR4 and ACKR3 with Novel Engineered Chemokines
The chemokine CXCL12 and its G protein-coupled receptors CXCR4 and ACKR3 are implicated in cancer and inflammatory and autoimmune disorders and are targets of numerous antagonist discovery efforts. Here, we describe a series of novel, high affinity CXCL12-based modulators of CXCR4 and ACKR3 generate...
Enregistré dans:
| Publié dans: | J Biol Chem |
|---|---|
| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566214/ https://ncbi.nlm.nih.gov/pubmed/26216880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.675108 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|