Antagonism of the Chemokine Receptors CXCR3 and CXCR4 Reduces the Pathology of Experimental Autoimmune Encephalomyelitis

Chemokines regulate lymphocyte trafficking under physiologic and pathologic conditions. In this study, we have investigated the role of CXCR3 and CXCR4 in the activation of T lymphocytes and their migration to the central nervous system (CNS) using novel mutant chemokines to antagonize CXCR3 and CXC...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Kohler, Rachel E., Comerford, Iain, Townley, Scott, Haylock‐Jacobs, Sarah, Clark‐Lewis, Ian, McColl, Shaun R.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095644/
https://ncbi.nlm.nih.gov/pubmed/18422759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00154.x
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