Antagonism of the Chemokine Receptors CXCR3 and CXCR4 Reduces the Pathology of Experimental Autoimmune Encephalomyelitis

Chemokines regulate lymphocyte trafficking under physiologic and pathologic conditions. In this study, we have investigated the role of CXCR3 and CXCR4 in the activation of T lymphocytes and their migration to the central nervous system (CNS) using novel mutant chemokines to antagonize CXCR3 and CXC...

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Vydáno v:Brain Pathol
Hlavní autoři: Kohler, Rachel E., Comerford, Iain, Townley, Scott, Haylock‐Jacobs, Sarah, Clark‐Lewis, Ian, McColl, Shaun R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095644/
https://ncbi.nlm.nih.gov/pubmed/18422759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2008.00154.x
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