Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors

Chemokines play critical roles in numerous physiological and pathological processes through their action on seven-transmembrane (TM) receptors. The N-terminal domain of chemokines, which is a key determinant of signaling via its binding within a pocket formed by receptors’ TM helices, can be the tar...

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Veröffentlicht in:J Leukoc Biol
Hauptverfasser: Jaracz-Ros, Agnieszka, Bernadat, Guillaume, Cutolo, Pasquale, Gallego, Carmen, Gustavsson, Martin, Cecon, Erika, Baleux, Françoise, Kufareva, Irina, Handel, Tracy M., Bachelerie, Françoise, Levoye, Angélique
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7540625/
https://ncbi.nlm.nih.gov/pubmed/32374043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.2MA0320-383RR
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