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Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12

Atypical chemokine receptors do not mediate chemotaxis or G protein signaling, but they recruit arrestin. They also efficiently scavenge their chemokine ligands, thereby contributing to gradient maintenance and termination. ACKR3, also known as CXCR7, binds and degrades the constitutive chemokine CX...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Benredjem, Besma, Girard, Mélanie, Rhainds, David, St.-Onge, Geneviève, Heveker, Nikolaus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217689/
https://ncbi.nlm.nih.gov/pubmed/27875312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762252
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