Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3

BACKGROUND AND PURPOSE: Chemokines and their receptors form an intricate interaction and signalling network that plays critical roles in various physiological and pathological cellular processes. The high promiscuity and apparent redundancy of this network makes probing individual chemokine/receptor...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Szpakowska, Martyna, Nevins, Amanda M, Meyrath, Max, Rhainds, David, D'huys, Thomas, Guité‐Vinet, François, Dupuis, Nadine, Gauthier, Pierre‐Arnaud, Counson, Manuel, Kleist, Andrew, St‐Onge, Geneviève, Hanson, Julien, Schols, Dominique, Volkman, Brian F, Heveker, Nikolaus, Chevigné, Andy
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900987/
https://ncbi.nlm.nih.gov/pubmed/29272550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14132
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