The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and stress by activating opioid receptors, currently classified into four subtypes. Here we demonstrate that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines, is a broad-spectrum scavenger of...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Meyrath, Max, Szpakowska, Martyna, Zeiner, Julian, Massotte, Laurent, Merz, Myriam P., Benkel, Tobias, Simon, Katharina, Ohnmacht, Jochen, Turner, Jonathan D., Krüger, Rejko, Seutin, Vincent, Ollert, Markus, Kostenis, Evi, Chevigné, Andy
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305236/
https://ncbi.nlm.nih.gov/pubmed/32561830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16664-0
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