The atypical chemokine receptor ACKR3/CXCR7 is a broad-spectrum scavenger for opioid peptides

Endogenous opioid peptides and prescription opioid drugs modulate pain, anxiety and stress by activating opioid receptors, currently classified into four subtypes. Here we demonstrate that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines, is a broad-spectrum scavenger of...

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Vydáno v:Nat Commun
Hlavní autoři: Meyrath, Max, Szpakowska, Martyna, Zeiner, Julian, Massotte, Laurent, Merz, Myriam P., Benkel, Tobias, Simon, Katharina, Ohnmacht, Jochen, Turner, Jonathan D., Krüger, Rejko, Seutin, Vincent, Ollert, Markus, Kostenis, Evi, Chevigné, Andy
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7305236/
https://ncbi.nlm.nih.gov/pubmed/32561830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16664-0
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