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Mutational Analysis of Atypical Chemokine Receptor 3 (ACKR3/CXCR7) Interaction with Its Chemokine Ligands CXCL11 and CXCL12

Atypical chemokine receptors do not mediate chemotaxis or G protein signaling, but they recruit arrestin. They also efficiently scavenge their chemokine ligands, thereby contributing to gradient maintenance and termination. ACKR3, also known as CXCR7, binds and degrades the constitutive chemokine CX...

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Vydáno v:J Biol Chem
Hlavní autoři: Benredjem, Besma, Girard, Mélanie, Rhainds, David, St.-Onge, Geneviève, Heveker, Nikolaus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5217689/
https://ncbi.nlm.nih.gov/pubmed/27875312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762252
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