Exploiting Agonist Biased Signaling of Chemokines to Target Cancer

Por Roy, Ishan, Getschman, Anthony E., Volkman, Brian F., Dwinell, Michael B.
Publicado no Mol Carcinog (2016)

Differences in Sulfotyrosine Binding amongst CXCR1 and CXCR2 Chemokine Ligands

Por Moussouras, Natasha A., Getschman, Anthony E., Lackner, Emily R., Veldkamp, Christopher T., Dwinell, Michael B., Volkman, Brian F.
Publicado no Int J Mol Sci (2017)

Structural Analysis of a Novel Small Molecule Ligand Bound to the CXCL12 Chemokine

Por Smith, Emmanuel W., Liu, Yan, Getschman, Anthony E., Peterson, Francis C., Ziarek, Joshua J., Li, Rongshi, Volkman, Brian F., Chen, Yu
Publicado no J Med Chem (2014)

New paradigms in chemokine receptor signal transduction: moving beyond the two-site model

Por Kleist, Andrew B., Getschman, Anthony E., Ziarek, Joshua J., Nevins, Amanda M., Gauthier, Pierre-Arnaud, Chevigné, Andy, Szpakowska, Martyna, Volkman, Brian F.
Publicado no Biochem Pharmacol (2016)

Sulfopeptide probes of the CXCR4/CXCL12 interface reveal oligomer-specific contacts and chemokine allostery

Por Ziarek, Joshua J., Getschman, Anthony E., Butler, Stephen J., Taleski, Deni, Stephens, Bryan, Kufareva, Irina, Handel, Tracy M., Payne, Richard J., Volkman, Brian F.
Publicado em 2013

Structure-based identification of novel ligands targeting multiple sites within a chemokine-G protein–coupled receptor interface

Por Smith, Emmanuel W, Nevins, Amanda M, Qiao, Zhen, Liu, Yan, Getschman, Anthony E, Vankayala, Sai L, Kemp, M Trent, Peterson, Francis C, Li, Rongshi, Volkman, Brian F, Chen, Yu
Publicado no J Med Chem (2016)

CCR7 Sulfotyrosine Enhances CCL21 Binding

Por Phillips, Andrew J., Taleski, Deni, Koplinski, Chad A., Getschman, Anthony E., Moussouras, Natasha A., Richard, Amanda M., Peterson, Francis C., Dwinell, Michael B., Volkman, Brian F., Payne, Richard J., Veldkamp, Christopher T.
Publicado no Int J Mol Sci (2017)

Pancreatic cancer cell migration and metastasis is regulated by chemokine-biased agonism and bioenergetic signaling

Por Roy, Ishan, McAllister, Donna M., Gorse, Egal, Dixon, Kate, Piper, Clinton T., Zimmerman, Noah P., Getschman, Anthony E., Tsai, Susan, Engle, Dannielle D., Evans, Douglas B., Volkman, Brian F., Kalyanaraman, Balaraman, Dwinell, Michael B.
Publicado no Cancer Res (2015)