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Pancreatic cancer cell migration and metastasis is regulated by chemokine-biased agonism and bioenergetic signaling

Patients with pancreatic ductal adenocarcinoma (PDAC) invariably succumb to metastatic disease, but the underlying mechanisms that regulate PDAC cell movement and metastasis remain little understood. In this study, we investigated the effects of the chemokine gene CXCL12, which is silenced in PDAC t...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Roy, Ishan, McAllister, Donna M., Gorse, Egal, Dixon, Kate, Piper, Clinton T., Zimmerman, Noah P., Getschman, Anthony E., Tsai, Susan, Engle, Dannielle D., Evans, Douglas B., Volkman, Brian F., Kalyanaraman, Balaraman, Dwinell, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4560104/
https://ncbi.nlm.nih.gov/pubmed/26330165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2645
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