Profiling and targeting of cellular bioenergetics: inhibition of pancreatic cancer cell proliferation

BACKGROUND: Targeting both mitochondrial bioenergetics and glycolysis pathway is an effective way to inhibit proliferation of tumour cells, including those that are resistant to conventional chemotherapeutics. METHODS: In this study, using the Seahorse 96-well Extracellular Flux Analyzer, we mapped...

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Detalhes bibliográficos
Main Authors: Cheng, G, Zielonka, J, McAllister, D, Tsai, S, Dwinell, M B, Kalyanaraman, B
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4090735/
https://ncbi.nlm.nih.gov/pubmed/24867695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.272
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