Thermodynamic and kinetic design principles for amyloid-aggregation inhibitors

Understanding the mechanism of action of compounds capable of inhibiting amyloid-fibril formation is critical to the development of potential therapeutics against protein-misfolding diseases. A fundamental challenge for progress is the range of possible target species and the disparate timescales in...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Michaels, Thomas C. T., Šarić, Andela, Meisl, Georg, Heller, Gabriella T., Curk, Samo, Arosio, Paolo, Linse, Sara, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P. J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2020
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7533883/
https://ncbi.nlm.nih.gov/pubmed/32929030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2006684117
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia