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Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide

Mapping energy landscapes has proved to be a powerful tool for studying reaction mechanisms. Many complex biomolecular assembly processes, however, have remained challenging to access using this approach, including the aggregation of peptides and proteins into amyloid fibrils implicated in various d...

詳細記述

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書誌詳細
出版年:Nat Chem
主要な著者: Cohen, Samuel I. A., Cukalevski, Risto, Michaels, Thomas. C. T., Šarić, Anđela, Törnquist, Mattias, Vendruscolo, Michele, Dobson, Christopher M., Buell, Alexander K., Knowles, Tuomas P. J., Linse, Sara
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5911155/
https://ncbi.nlm.nih.gov/pubmed/29581486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0023-x
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