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Distinct thermodynamic signature of oligomer generation in the aggregation of the amyloid-β peptide
Mapping energy landscapes has proved to be a powerful tool for studying reaction mechanisms. Many complex biomolecular assembly processes, however, have remained challenging to access using this approach, including the aggregation of peptides and proteins into amyloid fibrils implicated in various d...
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| Publicado en: | Nat Chem |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5911155/ https://ncbi.nlm.nih.gov/pubmed/29581486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-018-0023-x |
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