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Identification of on- and off-pathway oligomers in amyloid fibril formation

The misfolding and aberrant aggregation of proteins into fibrillar structures is a key factor in some of the most prevalent human diseases, including diabetes and dementia. Low molecular weight oligomers are thought to be a central factor in the pathology of these diseases, as well as critical inter...

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Bibliografiska uppgifter
I publikationen:Chem Sci
Huvudupphovsmän: Dear, Alexander J., Meisl, Georg, Šarić, Anđela, Michaels, Thomas C. T., Kjaergaard, Magnus, Linse, Sara, Knowles, Tuomas P. J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Royal Society of Chemistry 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7480182/
https://ncbi.nlm.nih.gov/pubmed/32953019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9sc06501f
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