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The role of fibril structure and surface hydrophobicity in secondary nucleation of amyloid fibrils
Crystals, nanoparticles, and fibrils catalyze the generation of new aggregates on their surface from the same type of monomeric building blocks as the parent assemblies. This secondary nucleation process can be many orders of magnitude faster than primary nucleation. In the case of amyloid fibrils a...
Gardado en:
| Publicado en: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7568274/ https://ncbi.nlm.nih.gov/pubmed/33004626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2002956117 |
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