Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication

The aggregation of the amyloid β peptide (Aβ) into amyloid fibrils is a defining characteristic of Alzheimer’s disease. Because of the complexity of this aggregation process, effective therapeutic inhibitors will need to target the specific microscopic steps that lead to the production of neurotoxic...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Munke, Anna, Persson, Jonas, Weiffert, Tanja, De Genst, Erwin, Meisl, Georg, Arosio, Paolo, Carnerup, Anna, Dobson, Christopher M., Vendruscolo, Michele, Knowles, Tuomas P. J., Linse, Sara
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2017
Gaiak:
Physical Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488933/
https://ncbi.nlm.nih.gov/pubmed/28584111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700407114
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