A conditional mouse expressing an activating mutation in NRF2 displays hyperplasia of the upper gastrointestinal tract and decreased white adipose tissue

Activation of the nuclear factor (erythroid-derived 2)-like 2 (NFE2L2 or NRF2) transcription factor is a critical and evolutionarily conserved cellular response to oxidative stress, metabolic stress, and xenobiotic insult. Deficiency of NRF2 results in hypersensitivity to a variety of stressors, whe...

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Detaylı Bibliyografya
Yayımlandı:J Pathol
Asıl Yazarlar: Bowman, Brittany M., Montgomery, Stephanie A., Schrank, Travis P., Simon, Jeremy M., Ptacek, Travis S., Tamir, Tigist Y., Muvlaney, Kathleen M., Weir, Seth J., Nguyen, Tuong T., Murphy, Ryan M., Makowski, Liza, Hayes, D. Neil., Chen, Xiaoxin L., Randell, Scott H., Weissman, Bernard E., Major, Michael B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511428/
https://ncbi.nlm.nih.gov/pubmed/32619021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5504
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