Direct kinetic fingerprinting and digital counting of single protein molecules

The sensitive and accurate quantification of protein biomarkers plays important roles in clinical diagnostics and biomedical research. Sandwich ELISA and its variants accomplish the capture and detection of a target protein via two antibodies that tightly bind at least two distinct epitopes of the s...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Chatterjee, Tanmay, Knappik, Achim, Sandford, Erin, Tewari, Muneesh, Choi, Sung Won, Strong, William B., Thrush, Evan P., Oh, Kenneth J., Liu, Ning, Walter, Nils G., Johnson-Buck, Alexander
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502736/
https://ncbi.nlm.nih.gov/pubmed/32868420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008312117
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