Direct kinetic fingerprinting and digital counting of single protein molecules

The sensitive and accurate quantification of protein biomarkers plays important roles in clinical diagnostics and biomedical research. Sandwich ELISA and its variants accomplish the capture and detection of a target protein via two antibodies that tightly bind at least two distinct epitopes of the s...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Chatterjee, Tanmay, Knappik, Achim, Sandford, Erin, Tewari, Muneesh, Choi, Sung Won, Strong, William B., Thrush, Evan P., Oh, Kenneth J., Liu, Ning, Walter, Nils G., Johnson-Buck, Alexander
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2020
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502736/
https://ncbi.nlm.nih.gov/pubmed/32868420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008312117
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