Rapid kinetic fingerprinting of single nucleic acid molecules by a FRET-based dynamic nanosensor

Biofluid-derived cell-free nucleic acids such as microRNAs (miRNAs) and circulating tumor-derived DNAs (ctDNAs) have emerged as promising disease biomarkers. Conventional detection of these biomarkers by digital PCR and next generation sequencing, although highly sensitive, requires time-consuming e...

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Bibliographic Details
Published in:Biosens Bioelectron
Main Authors: Khanna, Kunal, Mandal, Shankar, Blanchard, Aaron T., Tewari, Muneesh, Johnson-Buck, Alexander, Walter, Nils G.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295208/
https://ncbi.nlm.nih.gov/pubmed/34171818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bios.2021.113433
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