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A guide to nucleic acid detection by single-molecule kinetic fingerprinting

Conventional methods for detecting small quantities of nucleic acids require amplification by the polymerase chain reaction (PCR), which necessitates prior purification and introduces copying errors. While amplification-free methods do not have these shortcomings, they are generally orders of magnit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Methods
Hauptverfasser: Johnson-Buck, Alexander, Li, Jieming, Tewari, Muneesh, Walter, Nils G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6325009/
https://ncbi.nlm.nih.gov/pubmed/30099084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2018.08.002
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