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Kinetic fingerprinting to identify and count single nucleic acids
MicroRNAs (miRNAs) have emerged as promising diagnostic biomarkers. We introduce a kinetic fingerprinting approach called Single Molecule Recognition through Equilibrium Poisson Sampling (SiMREPS) for the amplification-free counting of single unlabeled miRNA molecules, which circumvents thermodynami...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4559481/ https://ncbi.nlm.nih.gov/pubmed/26098451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3246 |
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