Direct kinetic fingerprinting and digital counting of single protein molecules

The sensitive and accurate quantification of protein biomarkers plays important roles in clinical diagnostics and biomedical research. Sandwich ELISA and its variants accomplish the capture and detection of a target protein via two antibodies that tightly bind at least two distinct epitopes of the s...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Chatterjee, Tanmay, Knappik, Achim, Sandford, Erin, Tewari, Muneesh, Choi, Sung Won, Strong, William B., Thrush, Evan P., Oh, Kenneth J., Liu, Ning, Walter, Nils G., Johnson-Buck, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2020
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502736/
https://ncbi.nlm.nih.gov/pubmed/32868420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2008312117
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