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Therapeutic modulation of inflammasome pathways

Inflammasomes are macromolecular complexes formed in response to pathogen‐associated molecular patterns (PAMPs) and danger‐associated molecular patterns (DAMPs) that drive maturation of the pro‐inflammatory cytokines interleukin (IL)‐1β and IL‐18, and cleave gasdermin D (GSDMD) for induction of pyro...

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Bibliografiske detaljer
Udgivet i:Immunol Rev
Main Authors: Chauhan, Dhruv, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497261/
https://ncbi.nlm.nih.gov/pubmed/32770571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12908
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