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Therapeutic modulation of inflammasome pathways

Inflammasomes are macromolecular complexes formed in response to pathogen‐associated molecular patterns (PAMPs) and danger‐associated molecular patterns (DAMPs) that drive maturation of the pro‐inflammatory cytokines interleukin (IL)‐1β and IL‐18, and cleave gasdermin D (GSDMD) for induction of pyro...

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Détails bibliographiques
Publié dans:Immunol Rev
Auteurs principaux: Chauhan, Dhruv, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497261/
https://ncbi.nlm.nih.gov/pubmed/32770571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12908
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