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Therapeutic modulation of inflammasome pathways

Inflammasomes are macromolecular complexes formed in response to pathogen‐associated molecular patterns (PAMPs) and danger‐associated molecular patterns (DAMPs) that drive maturation of the pro‐inflammatory cytokines interleukin (IL)‐1β and IL‐18, and cleave gasdermin D (GSDMD) for induction of pyro...

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Detalles Bibliográficos
Publicado en:Immunol Rev
Main Authors: Chauhan, Dhruv, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497261/
https://ncbi.nlm.nih.gov/pubmed/32770571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12908
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