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Inflammasomes: Caspase-1-Activating Platforms with Critical Roles in Host Defense

Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections. Inflammasome activation induces inflammation through secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18 and through extracel...

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Detalhes bibliográficos
Main Authors: Vande Walle, Lieselotte, Lamkanfi, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109324/
https://ncbi.nlm.nih.gov/pubmed/21687402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2011.00003
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