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Deregulated inflammasome signaling in disease
Inflammasomes are multi-protein complexes that sense microbial molecules and endogenous danger signals in intracellular compartments. Inflammasome assembly results in caspase-1 activation, which in turn drives maturation and secretion of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3170132/ https://ncbi.nlm.nih.gov/pubmed/21884175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-065X.2011.01042.x |
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