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The Alzheimer’s Amyloid-β(1–42) Peptide Forms Off-Pathway Oligomers and Fibrils that are Distinguished Structurally by Intermolecular Organization

Increasing evidence suggests that soluble aggregates of amyloid-β (Aβ) initiate the neurotoxicity that eventually leads to dementia in Alzheimer’s disease. Knowledge of soluble aggregate structures will enhance our understanding of the relationship between structures and toxicities. Our group has re...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Tay, William M., Huang, Danting, Rosenberry, Terrone L., Paravastu, Anant K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490758/
https://ncbi.nlm.nih.gov/pubmed/23583777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.003
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