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Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils
Deposition of Aβ in the brain is a pathological hallmark of Alzheimer's disease. There are two major isoforms of Aβ: the 42-residue Aβ42 and the 40-residue Aβ40. The only difference between Aβ42 and Aβ40 is that Aβ42 has two extra residues at the C-terminus. The amyloid plaques in Alzheimer...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716832/ https://ncbi.nlm.nih.gov/pubmed/23406382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12202 |
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