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Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

Deposition of Aβ in the brain is a pathological hallmark of Alzheimer's disease. There are two major isoforms of Aβ: the 42-residue Aβ42 and the 40-residue Aβ40. The only difference between Aβ42 and Aβ40 is that Aβ42 has two extra residues at the C-terminus. The amyloid plaques in Alzheimer...

詳細記述

保存先:
書誌詳細
主要な著者: Gu, Lei, Guo, Zhefeng
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716832/
https://ncbi.nlm.nih.gov/pubmed/23406382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12202
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