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Alzheimer’s Aβ42 and Aβ40 form mixed oligomers with direct molecular interactions
Formation of Aβ oligomers and fibrils plays a central role in the pathogenesis of Alzheimer’s disease. There are two major forms of Aβ in the brain: Aβ42 and Aβ40. Aβ42 is the major component of the amyloid plaques, but the overall abundance of Aβ40 is several times that of Aβ42. In vitro experiment...
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| Publicado en: | Biochem Biophys Res Commun |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7785691/ https://ncbi.nlm.nih.gov/pubmed/33272573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2020.11.092 |
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