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Amyloid β-peptides 1–40 and 1–42 form oligomers with mixed β-sheets

Two main amyloid-β peptides of different length (Aβ(40) and Aβ(42)) are involved in Alzheimer's disease. Their relative abundance is decisive for the severity of the disease and mixed oligomers may contribute to the toxic species. However, little is know about the extent of mixing. To study whe...

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Foilsithe in:Chem Sci
Main Authors: Baldassarre, Maurizio, Baronio, Cesare M., Morozova-Roche, Ludmilla A., Barth, Andreas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Royal Society of Chemistry 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5857929/
https://ncbi.nlm.nih.gov/pubmed/29568473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc01743j
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