Out-of-register parallel β-sheets and antiparallel β-sheets coexist in 150 kDa oligomers formed by Amyloid-β(1–42)

We present solid-state NMR measurements of β-strand secondary structure and inter-strand organization within a 150 kDa oligomeric aggregate of the 42-residue variant of the Alzheimer’s amyloid-β peptide (Aβ(1–42)). We build upon our previous report of a β-strand spanned by residues 30–42, which arra...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Gao, Yuan, Guo, Cong, Watzlawik, Jens O., Randolph, Peter S., Lee, Elizabeth J., Huang, Danting, Stagg, Scott M., Zhou, Huan-Xiang, Rosenberry, Terrone L., Paravastu, Anant K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387221/
https://ncbi.nlm.nih.gov/pubmed/32470558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.05.018
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados