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Antiparallel β-sheet structure within the C-terminal region of 42-residue Alzheimer’s β-amyloid peptides when they form 150 kDa oligomers

Understanding the molecular structures of amyloid-β (Aβ) oligomers and underlying assembly pathways will advance our understanding of Alzheimer’s disease (AD) at the molecular level. This understanding could contribute to disease prevention, diagnosis, and treatment strategies, as oligomers play a c...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Huang, Danting, Zimmerman, Maxwell I., Martin, Patricia K., Nix, A. Jeremy, Rosenberry, Terrone L., Paravastu, Anant K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457621/
https://ncbi.nlm.nih.gov/pubmed/25889972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.04.004
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