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Antiparallel β-sheet structure within the C-terminal region of 42-residue Alzheimer’s β-amyloid peptides when they form 150 kDa oligomers

Understanding the molecular structures of amyloid-β (Aβ) oligomers and underlying assembly pathways will advance our understanding of Alzheimer’s disease (AD) at the molecular level. This understanding could contribute to disease prevention, diagnosis, and treatment strategies, as oligomers play a c...

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Bibliografische gegevens
Gepubliceerd in:J Mol Biol
Hoofdauteurs: Huang, Danting, Zimmerman, Maxwell I., Martin, Patricia K., Nix, A. Jeremy, Rosenberry, Terrone L., Paravastu, Anant K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457621/
https://ncbi.nlm.nih.gov/pubmed/25889972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.04.004
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