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The Alzheimer’s Amyloid-β(1–42) Peptide Forms Off-Pathway Oligomers and Fibrils that are Distinguished Structurally by Intermolecular Organization

Increasing evidence suggests that soluble aggregates of amyloid-β (Aβ) initiate the neurotoxicity that eventually leads to dementia in Alzheimer’s disease. Knowledge of soluble aggregate structures will enhance our understanding of the relationship between structures and toxicities. Our group has re...

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Vydáno v:J Mol Biol
Hlavní autoři: Tay, William M., Huang, Danting, Rosenberry, Terrone L., Paravastu, Anant K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7490758/
https://ncbi.nlm.nih.gov/pubmed/23583777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.003
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