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The Alzheimer’s Amyloid-β(1–42) Peptide Forms Off-Pathway Oligomers and Fibrils that are Distinguished Structurally by Intermolecular Organization
Increasing evidence suggests that soluble aggregates of amyloid-β (Aβ) initiate the neurotoxicity that eventually leads to dementia in Alzheimer’s disease. Knowledge of soluble aggregate structures will enhance our understanding of the relationship between structures and toxicities. Our group has re...
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| Pubblicato in: | J Mol Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7490758/ https://ncbi.nlm.nih.gov/pubmed/23583777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.04.003 |
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