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A Conserved Proline Hinge Mediates Helix Dynamics and Activation of Rhodopsin
Despite high-resolution crystal structures of both inactive and active G protein-coupled receptors (GPCRs), it is still not known how ligands trigger the large structural change on the intracellular side of the receptor since the conformational changes that occur within the extracellular ligand-bind...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484155/ https://ncbi.nlm.nih.gov/pubmed/32470317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.05.004 |
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