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Free backbone carbonyls mediate rhodopsin activation
Conserved prolines in the transmembrane helices of G protein-coupled receptors (GPCRs) are often considered to function as hinges that divide the helix into two segments capable of independent motion. Depending on their potential to hydrogen-bond, the free C=O groups associated with these prolines c...
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Publicado no: | Nat Struct Mol Biol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4972713/ https://ncbi.nlm.nih.gov/pubmed/27376589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3257 |
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