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Retinal orientation and interactions in rhodopsin reveal a two-stage trigger mechanism for activation
The 11-cis retinal chromophore is tightly packed within the interior of the visual receptor rhodopsin and isomerizes to the all-trans configuration following absorption of light. The mechanism by which this isomerization event drives the outward rotation of transmembrane helix H6, a hallmark of acti...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025775/ https://ncbi.nlm.nih.gov/pubmed/27585742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12683 |
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